CLOBETASOLE PROPIONATE USP
TEMOVATE (clobetasol propionate) Scalp Application contains the active compound clobetasol propionate, a synthetic , for topical dermatologic use. Clobetasol, an of prednisolone, has a high degree of activity and a slight degree of mineralocorticoid activity.
Chemically, clobetasol propionate is (11B,16B)-21- chioro-9-fluoro-11 -hydroxy-16-methyl-17-(1 -oxo- propoxy)pregna-1,4-diene-3,20-dione, and it has the following structural formula:
Clobetasol propionate has the formula C H CIFO and a molecular weight of 467. It is a white to cream-colored crystalline powder insoluble in water.
TEMOVATE Scalp (clobetasol propionate scalp application) Application contains clobetasol propionate 0.5 mg/g in a base of purified water, iso propyl (39.3%), carbomer 934P, and hydroxide.